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Glaucoma in Dogs – Your Complete E-Guide

Glaucoma in dogs is a painful condition caused by increased pressure (intraocular pressure – IOP) inside the eye. To best understand glaucoma in dogs, you really need to know more about your dog’s eye anatomy. Don’t worry. I won’t bore you to tears (pun intended).

There are 3 categories of canine glaucoma including primary, secondary (most common), and congenital. Unlike the type of glaucoma you or I might get, canine glaucoma is much more likely to cause blindness. By the time you’re finished reading this post, you’ll understand why.


Glaucoma in Dogs – The Ciliary Body
The ciliary body plays an important role because

produces the fluid that keeps the shape of the eye

provides vital nutrients and oxygen through the fluid it produces

suspends the eye’s lens in place

In a healthy dog eye, the liquid drains back into the dog’s system through an opening between the cornea and the iris. The ciliary body does its own thing within the eye itself, working hard to maintain a healthy equilibrium.

Still can’t picture it?

Imagine overfilling a water balloon. The balloon is going to get larger and larger, creating pressure and compromising the balloon’s integrity. The same thing happens to the dog’s eye when normal drainage cannot take place.

This strain and pressure within the eye can eventually damage the optic nerve (and ganglion cells), causing blindness. Systemically, it’s thought that the increased intra-ocular pressure causes damage to the optic nerve, which then results in a loss of retinal ganglion cells.

Retinal Ganglion Cells

These cells (neurons) transmit image-forming and non-image forming communication between the retina and the brain. Each ganglion cell receives visual information from photo receptors.

I’m just going to come out and say that I don’t totally understand all of the complicated workings of each ganglion cell. As I mentioned above, I’m not a veterinarian. From what I can gather, however, these cells are an important part of the informational highway to the brain. They manage pupil function and transmit visual information.

Intra-ocular Pressure (IOP)

Both the optic nerve and retinal ganglion cells are damaged by the intra-ocular pressure of glaucoma in dogs. The damage caused typically results in partial or complete blindness.

Normal IOP in Dogs

Normal pressure in dogs ranges between 10 and 20 mmHg (millimeters of mercury). Pressures ranging between 30 and even 50 mmHg has been represented in dogs with glaucoma.

Primary and Secondary Glaucoma in Dogs

This type of glaucoma in dogs is usually caused by what’s known as “closed angle” glaucoma; however, (rarely) it can also be caused by open angle glaucoma.

Acute primary glaucoma can come on suddenly. What that happens, it is considered a medical emergency. If the eye isn’t treated immediately, loss of vision is likely.

Primary Closed Angle Glaucoma in Dogs (most common of the primary glaucoma type)

There are a lot of complicated medical terms to describe this process, but – essentially – the drainage angle becomes blocked by the iris. Primary glaucoma is caused by genetic defects that affect the eye.

Once the fluid is trapped inside, pressure (inter-ocular pressure or IOP) builds quickly within the eye. Veterinarians refer to this as “acute glaucoma”, which is a medical emergency.

When this happens, there is a very high chance that your dog will go blind in the affected eye.
If you’re up for some serious medical jargon, check out this article at Veterinarian Medical Center of Long Island website.

Read: Von Willebrand’s Disease in Dogs – Information You Can Use

Primary Open Angle Glaucoma in Dogs (least common)


This type is considered a genetic mutation causing the build-up of pressure within the eye. The condition prevents the fluid (aqueous humor) produced by the ciliary body from draining naturally. As a result, death occurs within the ganglion cells. 

As mentioned above, this isn’t particularly common, especially if breeders are carefully selecting dogs based on accurate DNA testing.

SECONDARY GLAUCOMA IN DOGS (Most Common)

This particular type of glaucoma works the same way, in that there is increased pressure within the eye. The causes, however, are typically due to disease (cancer, for example) or eye injuries.

Uveitis in Dogs

This is the medical term for the inflammation of the eye’s interior. Debris and scar tissue end up blocking the drainage angle in this case.

Tumors/Cancer

If tumors are present within the eye, they can cause blockage of the drainage angle.

Lens Dislocation

In this situation, the lens actually tips forward and blocks the drainage angle. This is another scenario in which fluid keeps going in, but has no way of getting out.

Blood Clot

This is known as intra-ocular bleeding in which a blood clot blocks the drainage area.

• Lens Injury

If the dog’s eye is seriously damaged, the lens proteins begin leaking into the eye. This creates an inflammatory condition. The swelling then blocks the drainage angle.

The Difficulty Associated with Early Diagnosis

It can be difficult to notice early signs of glaucoma in dogs. Unless it’s acute, the disease can progress slowly and the symptoms noticed can be passed off as a condition of ageing.  Your dog obviously can’t tell you about the pain, and unless he/she actually has a bulging eye or is really rubbing the area, you could easily miss the signs.

The most common signs of glaucoma in dogs are:

Eye pain

Some dogs do a pretty good job of hiding discomfort and others might begin pawing at the area immediately. If your dog moves his/her head away from you when you try to get close, or appears to be guarding or protecting the face, have it checked out by a licensed veterinarian!

Eye discharge

My golden retriever seems to have naturally watery eyes that causes a dark stain on her fur. If there were a problem with her eye, the discharge would increase and become much more obvious. Along with this, your dog might seem “down” or have the blues. Remember, glaucoma in dogs is a painful condition.

Off-Color

Take a second to look into your dog’s eyes. Do the corneas look grey, colorless, or even blue-tinged? If so, get your dog to a veterinarian as soon as possible.

Swelling

This is going to be pretty noticeable. As the disease advances, you’re going to see one, or both, of your dog’s eyes bulging. It might not be a lot, but you’ll notice a difference.

Other signs include:

  • • Blinking a lot.
  • • Reddened blood vessels
  • • Dilated pupil
  • • Pupil that doesn’t respond to light
  • • Partial or complete blindness in one eye.
glaucoma in dogs can cause blindness

Treatment Options for Glaucoma in Dogs

Here’s where things really get tricky. Once the veterinarian has diagnosed glaucoma (whether primary or secondary), the first thing that needs to be done is to remove pressure ASAP.

The quicker pressure is released, the less damage is done to the optic nerve. In addition, the release of pressure reduces pain.

Note: Opening the drain and keeping it open in animals is difficult and costly. Most people opt for medicine that helps reduce the fluid build-up.

Surgical removal of the eye (called enucleation) is typically reserved for end-stage glaucoma where blindness has occurred or is imminent.

There are several treatment options. The problem is the expense, commitment to lifelong treatment, and the fact that eventually, even the good eye will succumb. Eventual blindness is almost guaranteed.

Medicated Eye Drops

Glaucoma eye drops and pills are expensive and are usually used to preserve sight in the unaffected eye for as long as possible. They are also used temporarily in dogs waiting for surgery.

Complementary and Alternative Medicine

This involves using lifetime therapies using canine antioxidant vision supplements. There are a variety of available supplements (ask your veterinarian for a recommendation). These supplements typically contain:

• amino acids
• vitamins
• lutein
• Omega 3 fatty acids
• lycopene
• and other combinations of antioxidants

If the dog has gone completely blind in that eye, you still have a few options. Some people prefer to have the eye removed and the area stitched. It’s important to understand that regardless of whether the dog has vision or not, that eye is still going to cause pressure and intense pain.

Other Medical Treatment Options include:

-artificial lens and a drainage device

-insert an implant into the eye socket then stitch the lids shut. This helps to maintain the shape of the eye socket so that the dog doesn’t wind up with a sunken look.

-injection of a drug into the eye socket. This drug is designed to kill the fluid-producing cells. Doing this helps to keep the overall pressure down which would reduce the dog’s pain.

-Laser surgery is done only when the surgeon believes there is a reasonably strong chance that the dog will have vision in that eye for a while.

-remove the eye and replace with a black ball that serves as a device to keep the eye socket in shape and remove the chance of a sunken in appearance later on.

-The blind eye is replaced with a colorless ball that makes it look as if the dog still has a working eye.

SURGERY – When blindness is inevitable

When or if your dog loses his/her sight, you will have even bigger decisions to make. 

Cyclodestruction

This type of surgery generally utilizes a laser to reduce the production of aqueous humor.

Unfortunately, this type of surgery (because it is non-invasive) isn’t able to determine exactly how much the ciliary body has been destroyed. A lens implant is usually required post-surgery in order to prevent cataracts from forming later on.

Surgery to Increase Aqueous Humor Outflow

Shunts can be used through an implant and tubing that permits the fluid to drain effectively from the anterior chamber. This is a difficult procedure not proven to affect a positive long-term outcome. There are several possible complications associated with this surgery as well.

Enucleation

Depending on financial status and the type of aesthetic outcome desired, people generally choose this option because of it is effective and much less expensive. Essentially, this involves removing the eyeball.

A prosthesis can be inserted to improve the appearance and, by removing the eye, your dog is relieved of pain.

Intrascleral Prosthesis

A silicon ball is inserted within the eye resulting in a better appearance and few complications. It’s thought to have a 95% success rate.

Chemical Ablation

An injection of gentamicin (antibiotic) and dexamethasone (corticosteroid) is inserted directly into the ciliary body. Complications could include eye inflammation and retinal detachment.
 

Dogs DO Adjust to Vision Loss

People are surprised to learn that dogs bounce back very quickly. Partial or even total blindness can be overcome with a little patience and preparation around the house.

-Enable sound cues
-tactile cues
-scent cues
-lots of talk direction
-maintain routine
-create awareness so that other people treat the dog accordingly
-close off any danger zones (for example, stairs with baby gate)

Summary

While glaucoma in dogs isn’t life-threatening, it can cause pain and serious damage if not treated. As our dogs age, our responsibility to bring them for regular veterinarian check-ups increase.

The faster glaucoma is found and treated, the better. At the end of the day, I think we all want the same things for our dogs: The best life we can give them.

I hope you were able to find useful information here. If you enjoyed the post, please take a second to share. Make sure to come back often.

Questions? Please feel free to contact me directly at: [email protected]

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