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Prozac for Dogs -5 No-Fail Steps to Weaning

Veterinarians have been prescribing Prozac for years. Prozac (Fluoxetine) is only FDA approved for treating separation anxiety in dogs. The antidepressant, however, has also been used to treat obsessive compulsive disorder, some types of aggression, and anxiety disorders. The goal of prescribing Prozac for dogs is to help the dog achieve a mentally-balanced state. Over time, the hope is that the dog will be able to learn new behaviour. With a little retraining, exercise, good nutrition, and patience, dogs can overcome some of their biggest obstacles.

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Substitute the Drug for This

Sooner or later, you’ll need to wean your dog off Prozac.  When that time comes, you’ll want to seek advice from a licensed veterinarian.  Not all dogs are the same and not all dogs require the same weaning process. It’s always better to keep the process slow than go to fast. It takes several weeks for the medication to be fully effective and it takes several weeks (or more) to come off of it.

Prozac for dogs can really help your dog with extreme anxiety, but when the time comes to wean you might consider offering a little help. Rather than go “cold turkey”, try an anxiety wrap or music designed specifically to calm anxious dogs.

In addition to offering a helping hand with stress-reducing aids, you’ll want to follow some basic steps of weaning. Remember, please check with your veterinarian before attempting to wean your dog from Prozac on your own.

STEP 1:   Make Sure the Veterinarian is in the Loop Before Weaning Your Dog Off Prozac.

Prozac for dogs takes time to metabolize completely. Serious interactions can occur when mixing antidepressants with other medications, or when weaning too quickly. If you’ve decided it’s time for your dog to come off of the medication, be sure to schedule a visit with the veterinarian. Your veterinarian will be able to monitor your dog’s reaction and gauge the risk of withdrawal symptoms.

Do not attempt to wean your dog off of any medications, including antidepressants, without the advice of a licensed veterinarian.

Antidepressants help to alleviate things like separation anxiety and rage syndrome.  The problem with taking Prozac for dogs away too soon is that he/she may not have had enough time to process the new dog training/routine. In addition, weaning too quickly can cause unwanted side-effects.

STEP 2:  Consider This Technique

We worry about our dogs because they’re part of the family. As your dog begins to come off of the drug, you might begin holding onto a little anxiety of your own. Your dog can sense that! As you go through this process, it’s important to let go of your own fears. Over-protecting your dog doesn’t tell your dog that you love him, it tells your dog that there’s something to be afraid of.

I recommend guided meditation as a way to help yourself relax and refocus your energy. I’ve recently started guided meditation and it does wonder for the mind. You don’t have to be perfect, just willing to let your mind rest for a few minutes. You can always do it on your own, but I find the cues that come from audio really help me focus.

Reconditioning your own behavior is an important step on the path to your dog’s ultimate mental health.  Look at ways you could be contributing to your dog’s anxiety and work to change that.

Become The Leader of the Pack

If a dog doesn’t feel that there’s a pack leader available, his dominant behavior will take over. It’s a matter of safety in the wild.  Your dog might sleep on the bed, but deeply ingrained in his brain are thousands of years of DNA that continue to dictate what he needs to do to survive.

Simple behavioral changes could include:

  • Not engaging excitedly with your dog before leaving the house. Be calm, quiet, and confident.
  • Carve out time to walk and socialize your dog
  • Read books that offer expert advice on why dogs have anxiety and what you can do about it.

I know it’s not easy, especially if you have a rescue dog who has come into your home with a whole history wired into his brain.

Prozac for Dogs – Side Effects of Weaning

Side effects of Prozac for dogs can include stomach upset and loss of appetite. In rare cases, more serious effects could include seizures, itching, insomnia, and diarrhea. When weaning your dog from the drug, it’s important to remember that there could be withdrawal symptoms if done too quickly. Some withdrawal symptoms could mimic the behaviour you were trying to erase like anxiety and aggression.

It’s hard to know if your dog is actually experiencing withdrawal or if the old behaviour is rearing its ugly head. That’s one more reason why it’s important to keep in contact with your veterinarian. You’ll want a professional backing you up as you go through the process.

STEP 3:  Begin the Weaning Process

Remember, there’s no hurry. Assuming you’ve got the go-ahead from the veterinarian, here are the steps:

  • Decrease the original dose by 1/2 (one-half) for 4 weeks.  Monitor your dog, and if he continues to do well, halve the dose again after 4 weeks.
  • Wait and monitor for another 2 to 4 weeks.
  • At the end of 8 weeks, it should be safe to totally discontinue the medication.

Just like humans, dogs have different requirements. The size of your dog, the starting dose, and the dog’s health and behavior will all play into the weaning process. That’s why it’s always good to get some professional advice.

STEP 4:  Monitor Your Dog 

Continue to monitor your dog’s behavior and reactions for up to 4 more weeks after he or she has completely tapered. It’s important for you to monitor your own behavior as well.

Your dog needs to see you as the leader of the pack at all times. It’s hard to establish a new routine, but important to maintain the expectations you’ve given the dog.

When it comes right down to it, you have to decide if it’s safe to keep the dog. That’s not easy to be objective about! Sometimes antidepressants will go a long way in reducing fear and anxiety in such a way that the dog is able to relearn behavior. That’s exactly what you want.

Without a strong pack-leader, your dog reverts to the expectations of the wild.

When you give your dog the signal that you are in charge, your dog can relax and follow. A well-adjusted dog that gets appropriate exercise, discipline, and reward, is a powerful thing.

Step 5: Here’s The Real Secret to Success

Walking. It’s good for your dog and it’s good for you. Walking your dog helps release nervous energy. Walking a dog does more than tire your dog physically. It also exposes your dog to a variety of sights and smells that stimulate the brain. Think of it like getting rid of nervous energy from the brain.

How well do you learn new things if your mind is racing? Probably not many. It’s the same with your dog. Once he/she has a calm mind, your dog will be better able to function and learn.

A Lesson For You

At the end of the day, we all want happy, balanced, healthy dogs. There are some dogs that are just so wound up and nervous you have to wonder if they’re ever going to get better. It can happen but it takes work and dedication. As you go through the weaning process with your dog, remember to take it slowly. The more you do for your own anxiety, the better off your dog will be too.

Congratulations!  You’re on your way to weaning your dog successfully off of Prozac.

  • Pita says:

    pita’s home is changing from small noisy apartment to single family home with large yard. Dog is from another country

  • Lisa Theriault says:

    Hi Melanie,
    Based on research of the drug itself and the lengthy time it can take to wean, I created a post with details on how to go about getting started. I’m afraid I don’t have a specific url or site I can point you to. I always recommend talking to a licensed veterinarian before attempting this. It’s important to get medical feedback because it might not be the right time to wean, or…depending on a number of things….may need to be approached more cautiously or slowly.

    Thanks for the question!

  • cvee says:

    I’ve just started weaning my dog off Prozac.
    Unfortunately he was already on a half dose daily… and it’s not possible to half it again for purpose of weaning. So vet suggested giving every second day for a month. Does that seem reasonable or will it just cause more stress being on it for a day and off for a day?